Table 6 |
|||
|
WOMBAT activity classes used in the virtual screening experiments. |
|||
|
Activity class |
Active molecules |
Pairwise similarity |
|
|
|
|||
|
Renin inhibitors |
474 |
0.592 |
0.109 |
|
Protein kinase C inhibitors |
142 |
0.565 |
0.277 |
|
Matrix metalloprotease inhibitors |
694 |
0.444 |
0.148 |
|
Angiotensin II AT1 antagonists |
724 |
0.443 |
0.131 |
|
HIV protease inhibitors |
1128 |
0.442 |
0.146 |
|
Substance P antagonists |
558 |
0.427 |
0.127 |
|
Thrombin inhibitors |
421 |
0.418 |
0.144 |
|
5HT1A antagonists |
592 |
0.399 |
0.134 |
|
Factor Xa inhibitors |
842 |
0.394 |
0.124 |
|
5HT3 antagonists |
220 |
0.377 |
0.175 |
|
Acetylcholine esterase inhibitors |
503 |
0.373 |
0.155 |
|
D2 antagonists |
910 |
0.367 |
0.116 |
|
Phosphodiesterase inhibitors |
596 |
0.359 |
0.136 |
|
Cyclooxygenase inhibitors |
965 |
0.324 |
0.139 |
|
|
|||
|
Details as for Table 3. |
|||
|
Chen et al. Journal of Cheminformatics 2009 1:5 doi:10.1186/1758-2946-1-5 |
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